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Further Recommended Reading:
Fish Diseases | How to Treat Sick Fish
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Oregon Grape, Berberine for Aquarium Fish Treatment



Oregon Grape Root Plant for Aquarium Fish MedicationBerberine is a plant based alkaloid that has been used medicinally for a long time in both Ayurvedic and Chinese medicine.
The Berberine alkaloid is present many plants including: Hydrastis canadensis (goldenseal), Coptis chinensis (Coptis or goldenthread), Berberis vulgaris (barberry), Berberis aristata (tree turmeric), and most notably Berberis aquifolium (Oregon grape).

The berberine alkaloid is generally found in the roots, rhizomes, and stem bark of the plants.
Berberine extracts and extractions via boiling of dissolved chemicals in the plant roots have demonstrated significant antimicrobial activity against a variety of organisms including bacteria, viruses, fungi, protozoans, helminths, and chlamydia.

Currently, the predominant clinical uses of berberine in human use includes bacterial (especially of the gut) diarrhea, intestinal parasite infections, and ocular trachoma infections.
Oregon grape root has synergistic antibacterial, anti-inflammatory, and bile-stimulating properties as well.

The picture above shows an Oregon Grape Root Plant along with the rhizomous roots with their brilliant yellow pigment in the inner bark shown in the inset.



Aquarium or pond use of Oregon Grape Root is still in its infancy as of writing this article, however based on human use, and how this this product works, there is clearly a lot of promise as both a treatment of its own and as a back up to other treatment in wide ranging problems from Columnaris to internal parasites of fish.

Oregon Grape Root has potential to aid in antibiotic effectiveness in treatment of difficult to treat diseases such as Columnaris as it contains a specific multi drug resistance pump inhibitor (MDR Inhibitor).

Resistant bacteria work by utilizing a pumping mechanism in its cell that when antibiotics enter that cell the pump immediately pumps out the antibiotics so it can have no effect on the MRSA cell. Oregon Grape Root works by blocking the bacteria's ability to pump out antibiotics.
Quoted Reference: [1]

Here is a list of Potential Treatments using Powdered Oregon Grape Root:

  • Eye infections
  • External wounds
  • Mouth infections
  • Inflammation
  • Intestinal Parasites
  • Digestive issues, including Dropsy

Use; Solaray Oregon Grape Root CapsulesDo NOT use tinctures, rather powdered forms that are generally available in capsule form, although concentration can vary greatly (I recommend Solaray brand from Nutraceutical, but I have not tried evert brand either).

Current and experimental use is opening a 400 mg Oregon Grape Root Capsule into 10 gallons of water along with the antibiotics such as Nitrofurazone and Kanamycin. This can be added to the aquarium or a fish bath that also employs Methylene Blue and possibly other antibiotics (20-30 minutes in a fish bath).
Use in conjunction with other medications is suggested in most moderate to serious infections or internal worm infestations.


Organic Aquarium Medications; Oregon Grape Root

Aquarium, Fish Parasites, Worms; Treatment of Internal Nematodes

Oregon Grape; Wild Medicines

From medical herbalism to phytotherapy in dermatology: back to the future


I personally have had the best results from the Solaray brand of Grape Root capsules, likely do to purity of the powdered grape root in the capsules

Product Resource:
Solaray Oregon Grape Root

Suggested other aquarium information resources & products:

Fish Diseases, How to Treat Sick Fish
Fish Diseases | How to Treat Sick Fish

Aquarium Medications, Use of replacement UV Bulbs for disease prevention
Replacement Aquarium/Pond UV Bulbs

Replacement of your UV Sterilizer's UV Bulb/Lamp every six months with a true level 1 capable bulb is a MUST for optimum disease prevention and aid in Redox balance.

Aquarium Medications, do not purchase at Amazon
Purchasing Aquarium & Pond Equipment via Amazon

Amazon Reviews for Aquarium Products

Aquarium Medications, beware of aquarium forums for information
Aquarium Forums for Information such as LED Lighting, UV, Filters, more

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Blogger Unknown said...

I am trying this treatment on two sick bettas. One I know probably has early dropsy symptoms the other at minimum has septicemia (blood spot on fins). Both were lethargic and sitting at the bottom of the tank. They are getting bath of Kanamycian, grape root and methylene blue daily. The first day I did espsom salt but I forgot today. They also are getting kanymyacin treated food applied with focus and garlic juice. I can't be sure how much is staying on the food since it's dry. The one with septicemia is improving like overnight. The one with likely dropsy doesn't seem worse but not better either. Will post long term results later

9:32 PM  
Blogger Unknown said...

I also am increasing water changes because it seems to be advised on various sites. I am considering putting the grape root in the tank of the dropsy fish.

9:34 PM  
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